Cagrilintide 10 mg — analytical-grade research peptideNNC0174-0833 · 10 mg / vial
Fig. 01 · Specimen
Lyophilised kit
In the box
  • ·3 mL bacteriostatic water
  • ·10 × 1 mL insulin syringes
  • ·Alcohol swabs
MetabolicClass IINNC0174-0833CagriSema component

Cagrilintide 10 mg

Long-acting amylin analogue — GLP-1 stack partner.

Cagrilintide is a long-acting amylin analogue most widely investigated in combination with semaglutide under the CagriSema programme. Commonly stacked with GLP-1 receptor agonists in preclinical research.

Designation
NNC0174-0833
CAS no.
Not assigned
Molecular formula
C176H274N48O53
MW (Da)
3906.5
Residues
32
Purity
≥ 98.5%
Form
Lyophilised kit
Dose
10 mg / vial
Class
Class II
Dispatch · per unit
£105GBP
≈ €124 · 0.00194 BTC
1
In stock·Same-day dispatch (order by 09:30 UK)·Tracked24 Royal Mail £6.50·Not shipped to USA
Clinical status: Investigational. In Phase 3 development by Novo Nordisk (CagriSema — combined with semaglutide). Not approved standalone.
§ A Overview

What the peptide is.

Cagrilintide is a once-weekly amylin analogue developed by Novo Nordisk. Native amylin is a 37-residue pancreatic hormone co-secreted with insulin; its receptor activation slows gastric emptying, increases satiety, and modulates post-prandial glucagon.

Cagrilintide combines amylin-/calcitonin-receptor agonism with a long-acting pharmacokinetic profile via C20 fatty-diacid conjugation.

Proposed mechanism

Agonism at calcitonin-family receptors (CT, AMY1, AMY2, AMY3). Slows gastric emptying, enhances satiety, modulates glucagon.

§ B Laboratory handling

Reconstitution, storage, and handling.

Lab-technical guidance for the researcher handling the material. Not therapeutic dosing, not administration guidance — those are not within the scope of this supply.

Reconstitution
Recommended solvent
Bacteriostatic water for injection (0.9% benzyl alcohol) — included with kit
Typical volume
1 – 2 mL
Notes
  • Inject diluent slowly down the side of the vial onto the cake.
  • Swirl gently — do not shake.
  • Solution should be clear and colourless. Discard if not.
Storage
Lyophilised
−20 °C, desiccated, protected from light. Stable at 15–25 °C for up to 30 days in transit.
Reconstituted
2–8 °C, original vial, consumed within 4 weeks.
Shelf life · sealed
24 months from date of manufacture when stored lyophilised at −20 °C.
Shelf life · reconstituted
Up to 4 weeks refrigerated.
Handling notes
  • Amylin peptides are historically fibril-prone — handle gently, no vigorous agitation.
  • Clear to very slightly opalescent solution is typical.
§ C Certificate of Analysis

This lot, documented.

Every shipment is accompanied by a signed four-page analytical report including the HPLC chromatogram, ESI-MS spectrum, purity calculation, and sample handling chain-of-custody.

The report you will receive is specific to the lot dispatched to you. The display below is a current representative example.

cagrilintide 10mg · batch.log
LIVE
04:22:11lot 26-04-A received ┈ 5.00 g
04:22:40weight check ┈ PASS ±0.4 mg
04:23:12sample → janoshik ┈ 50 mg
04:23:12tracking #jnk-9218334
05:18:03HPLC result ┈ 99.24 %
05:18:04MS obs 4729.42 Da ┈ PASS
05:18:05coa.pdf signed ┈ attached
05:18:06lot approved ┈ LIVE
janoshik.report.txt
SIGNED
REPORT ID     JA-26-04-012
SUBJECT       Cagrilintide 10 mg
DESIGNATION   NNC0174-0833
LOT           26-04-A
METHOD        RP-HPLC, ESI-MS
COLUMN        C18, 250 x 4.6 mm, 5 um
MOBILE PHASE  A: 0.1% TFA in H2O
              B: 0.1% TFA in ACN
GRADIENT      5 -> 65% B over 20 min
FLOW RATE     1.0 mL/min
DETECTION     UV 214 nm
INJECTION     20 uL @ 0.5 mg/mL
---
PURITY (A%)   98.50
MASS EXP.     3906.50 Da
MASS OBS.     3906.52 Da
---
CONCLUSION    Identity CONFIRMED · Purity PASS
SIGNED BY     J. Novak, MSc · Janoshik Analytical SVK
DATE          2026-04-11
representative chromatogram · A214 nmRT 8.42 min
Representative trace · Lot-specific COA included with every dispatch
purity≥ 98.5%
§ D Clinical trials

Registered clinical investigation.

Links below resolve to the ClinicalTrials.gov registry. Trial status reflects publicly disclosed information at the time of publication.

NCTPhaseTitleStatus
NCT05567796Phase 3REDEFINE-1: CagriSema in obesityOngoingRegistry ↗
NCT05813925Phase 3REDEFINE-2: CagriSema in obesity with T2DOngoingRegistry ↗
§ E Peer-reviewed studies

Research references for Cagrilintide 10 mg.

2 peer-reviewed publications. Links resolve to PubMed. DOIs are provided where available.

  1. [01]
    Enebo LB, et al.

    Cagrilintide with semaglutide for weight management — Phase 1b

    The Lancet · 2021
  2. [02]
    Lau DCW, et al.

    Once-weekly cagrilintide for weight management — Phase 2

    The Lancet · 2021
§ F Questions

About this peptide.

For general site, shipping, and payment questions see the full FAQ.

Q.Can this be stacked with other peptides in a research protocol?
A.Cagrilintide is most commonly paired with GLP-1 agonists in the published literature (the CagriSema programme). Each peptide is supplied separately; the decision to co-administer in a research protocol is the researcher's.
Research use only

This peptide is supplied by Omega Grade for in vitro laboratory research use. It is not a drug, food, cosmetic, or dietary supplement. It is not approved by the FDA, EMA, MHRA, PMDA, or any other regulatory authority for any therapeutic indication.

No claim of therapeutic benefit is made or implied. The material is not intended for human or veterinary consumption, administration, or any form of self-experimentation. By purchasing, you acknowledge the researcher terms and accept full responsibility for local import compliance and all handling.