Melanotan II 10 mg — analytical-grade research peptideMT-2 · 10 mg / vial
Fig. 01 · Specimen
Lyophilised kit
In the box
  • ·3 mL bacteriostatic water
  • ·10 × 1 mL insulin syringes
  • ·Alcohol swabs
DermalClass IIMT-2Melanotan 2

Melanotan II 10 mg

Melanocortin-receptor agonist — cyclic heptapeptide.

Melanotan II is a synthetic cyclic heptapeptide non-selective melanocortin-receptor agonist (MC1R / MC3R / MC4R / MC5R).

Designation
MT-2
CAS no.
121062-08-6
Molecular formula
C50H69N15O9
MW (Da)
1024.18
Residues
7
Purity
≥ 99.0%
Form
Lyophilised kit
Dose
10 mg / vial
Class
Class II
Dispatch · per unit
£49GBP
≈ €58 · 0.00091 BTC
1
In stock·Same-day dispatch (order by 09:30 UK)·Tracked24 Royal Mail £6.50·Not shipped to USA
Clinical status: Investigational. Early Phase 1 trials for photoprotection in the 1990s; no regulatory approval for any indication.
§ A Overview

What the peptide is.

Melanotan II was originally developed at the University of Arizona as a more potent, longer-acting analogue of α-MSH. The cyclic structure confers metabolic stability not present in native α-MSH.

Historical Phase 1 trials evaluated MT-II for photoprotection research. No progression to approved therapeutic use. MT-1 (afamelanotide) is the related linear analogue that reached approval for erythropoietic protoporphyria in specific jurisdictions.

Proposed mechanism

Non-selective agonism at melanocortin receptors MC1R, MC3R, MC4R, MC5R. MC1R activation modulates melanogenesis in melanocytes.

§ B Laboratory handling

Reconstitution, storage, and handling.

Lab-technical guidance for the researcher handling the material. Not therapeutic dosing, not administration guidance — those are not within the scope of this supply.

Reconstitution
Recommended solvent
Bacteriostatic water for injection (0.9% benzyl alcohol) — included with kit
Typical volume
1 – 2 mL
Notes
  • Inject diluent slowly down the side of the vial onto the cake.
  • Swirl gently — do not shake.
  • Solution should be clear and colourless. Discard if not.
Storage
Lyophilised
−20 °C, desiccated, protected from light. Stable at 15–25 °C for up to 30 days in transit.
Reconstituted
2–8 °C, original vial, consumed within 4 weeks.
Shelf life · sealed
24 months from date of manufacture when stored lyophilised at −20 °C.
Shelf life · reconstituted
Up to 4 weeks refrigerated.
Handling notes
  • Stable lyophilised. Standard peptide handling.
§ C Certificate of Analysis

This lot, documented.

Every shipment is accompanied by a signed four-page analytical report including the HPLC chromatogram, ESI-MS spectrum, purity calculation, and sample handling chain-of-custody.

The report you will receive is specific to the lot dispatched to you. The display below is a current representative example.

mt2 10mg · batch.log
LIVE
04:22:11lot 26-04-A received ┈ 5.00 g
04:22:40weight check ┈ PASS ±0.4 mg
04:23:12sample → janoshik ┈ 50 mg
04:23:12tracking #jnk-9218334
05:18:03HPLC result ┈ 99.24 %
05:18:04MS obs 4729.42 Da ┈ PASS
05:18:05coa.pdf signed ┈ attached
05:18:06lot approved ┈ LIVE
janoshik.report.txt
SIGNED
REPORT ID     JA-26-04-012
SUBJECT       Melanotan II 10 mg
DESIGNATION   MT-2
LOT           26-04-A
METHOD        RP-HPLC, ESI-MS
COLUMN        C18, 250 x 4.6 mm, 5 um
MOBILE PHASE  A: 0.1% TFA in H2O
              B: 0.1% TFA in ACN
GRADIENT      5 -> 65% B over 20 min
FLOW RATE     1.0 mL/min
DETECTION     UV 214 nm
INJECTION     20 uL @ 0.5 mg/mL
---
PURITY (A%)   99.00
MASS EXP.     1024.18 Da
MASS OBS.     1024.20 Da
---
CONCLUSION    Identity CONFIRMED · Purity PASS
SIGNED BY     J. Novak, MSc · Janoshik Analytical SVK
DATE          2026-04-11
representative chromatogram · A214 nmRT 8.42 min
Representative trace · Lot-specific COA included with every dispatch
purity≥ 99.0%
§ E Peer-reviewed studies

Research references for Melanotan II 10 mg.

1 peer-reviewed publications. Links resolve to PubMed. DOIs are provided where available.

  1. [01]
    Dorr RT, Lines R, Levine N, et al.

    Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide

    Life Sciences · 1996
§ F Questions

About this peptide.

For general site, shipping, and payment questions see the full FAQ.

Q.How does this differ from MT-1 (afamelanotide)?
A.MT-1 is a linear α-MSH analogue with MC1R selectivity and has reached approval for a narrow therapeutic indication (erythropoietic protoporphyria). MT-II is a cyclic non-selective melanocortin agonist — research use only.
Research use only

This peptide is supplied by Omega Grade for in vitro laboratory research use. It is not a drug, food, cosmetic, or dietary supplement. It is not approved by the FDA, EMA, MHRA, PMDA, or any other regulatory authority for any therapeutic indication.

No claim of therapeutic benefit is made or implied. The material is not intended for human or veterinary consumption, administration, or any form of self-experimentation. By purchasing, you acknowledge the researcher terms and accept full responsibility for local import compliance and all handling.