Sermorelin 10 mg — analytical-grade research peptideGRF(1-29) · 10 mg / vial
Fig. 01 · Specimen
Lyophilised kit
In the box
  • ·3 mL bacteriostatic water
  • ·10 × 1 mL insulin syringes
  • ·Alcohol swabs
Growth hormoneClass IGRF(1-29)Geref®

Sermorelin 10 mg

GHRH(1-29) analogue — the minimum fragment with full GH-releasing activity.

Sermorelin is the 29-amino-acid N-terminal fragment of GHRH — the minimum sequence for full GH-releasing activity.

Designation
GRF(1-29)
CAS no.
86168-78-7
Molecular formula
C149H246N44O42S
MW (Da)
3357.93
Residues
29
Purity
≥ 99.0%
Form
Lyophilised kit
Dose
10 mg / vial
Class
Class I
Dispatch · per unit
£85GBP
≈ €100 · 0.00157 BTC
1
In stock·Same-day dispatch (order by 09:30 UK)·Tracked24 Royal Mail £6.50·Not shipped to USA
Clinical status: Sermorelin was approved as Geref® for paediatric GH-deficiency evaluation; the commercial product was discontinued in 2008. No current approved indication. Research use only.
§ A Overview

What the peptide is.

Sermorelin (GRF 1-29) represents the minimum active fragment of GHRH. It has a short plasma half-life (~12 minutes) and was historically approved as a diagnostic agent for GH-deficiency evaluation.

The commercial product (Geref) was discontinued in 2008 — not for safety reasons. Widely used in preclinical GH-axis research today.

Proposed mechanism

Classical GHRH-receptor agonism; short-acting pulsatile stimulus to pituitary GH release.

§ B Laboratory handling

Reconstitution, storage, and handling.

Lab-technical guidance for the researcher handling the material. Not therapeutic dosing, not administration guidance — those are not within the scope of this supply.

Reconstitution
Recommended solvent
Bacteriostatic water for injection (0.9% benzyl alcohol) — included with kit
Typical volume
1 – 2 mL
Notes
  • Inject diluent slowly down the side of the vial onto the cake.
  • Swirl gently — do not shake.
  • Solution should be clear and colourless. Discard if not.
Storage
Lyophilised
−20 °C, desiccated, protected from light. Stable at 15–25 °C for up to 30 days in transit.
Reconstituted
2–8 °C, original vial, consumed within 4 weeks.
Shelf life · sealed
24 months from date of manufacture when stored lyophilised at −20 °C.
Shelf life · reconstituted
Up to 4 weeks refrigerated.
Handling notes
  • Standard peptide handling.
§ C Certificate of Analysis

This lot, documented.

Every shipment is accompanied by a signed four-page analytical report including the HPLC chromatogram, ESI-MS spectrum, purity calculation, and sample handling chain-of-custody.

The report you will receive is specific to the lot dispatched to you. The display below is a current representative example.

sermorelin 10mg · batch.log
LIVE
04:22:11lot 26-04-A received ┈ 5.00 g
04:22:40weight check ┈ PASS ±0.4 mg
04:23:12sample → janoshik ┈ 50 mg
04:23:12tracking #jnk-9218334
05:18:03HPLC result ┈ 99.24 %
05:18:04MS obs 4729.42 Da ┈ PASS
05:18:05coa.pdf signed ┈ attached
05:18:06lot approved ┈ LIVE
janoshik.report.txt
SIGNED
REPORT ID     JA-26-04-012
SUBJECT       Sermorelin 10 mg
DESIGNATION   GRF(1-29)
LOT           26-04-A
METHOD        RP-HPLC, ESI-MS
COLUMN        C18, 250 x 4.6 mm, 5 um
MOBILE PHASE  A: 0.1% TFA in H2O
              B: 0.1% TFA in ACN
GRADIENT      5 -> 65% B over 20 min
FLOW RATE     1.0 mL/min
DETECTION     UV 214 nm
INJECTION     20 uL @ 0.5 mg/mL
---
PURITY (A%)   99.00
MASS EXP.     3357.93 Da
MASS OBS.     3357.95 Da
---
CONCLUSION    Identity CONFIRMED · Purity PASS
SIGNED BY     J. Novak, MSc · Janoshik Analytical SVK
DATE          2026-04-11
representative chromatogram · A214 nmRT 8.42 min
Representative trace · Lot-specific COA included with every dispatch
purity≥ 99.0%
§ E Peer-reviewed studies

Research references for Sermorelin 10 mg.

1 peer-reviewed publications. Links resolve to PubMed. DOIs are provided where available.

  1. [01]
    Walker RF

    Sermorelin: a better approach to management of adult-onset growth hormone insufficiency?

    Clinical Interventions in Aging · 2006
§ F Questions

About this peptide.

For general site, shipping, and payment questions see the full FAQ.

Q.Why was Geref discontinued?
A.The withdrawal was commercial, not safety-related. More targeted GHRH analogues (tesamorelin) and alternative diagnostic approaches displaced the commercial indication.
Research use only

This peptide is supplied by Omega Grade for in vitro laboratory research use. It is not a drug, food, cosmetic, or dietary supplement. It is not approved by the FDA, EMA, MHRA, PMDA, or any other regulatory authority for any therapeutic indication.

No claim of therapeutic benefit is made or implied. The material is not intended for human or veterinary consumption, administration, or any form of self-experimentation. By purchasing, you acknowledge the researcher terms and accept full responsibility for local import compliance and all handling.