GLP-1
Glucagon-like peptide-1, an incretin hormone that regulates glucose and appetite.
Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted by intestinal L-cells in response to nutrient ingestion. It binds the GLP-1 receptor on pancreatic β-cells (stimulating glucose-dependent insulin secretion) and on neurons in the hypothalamus and brainstem (slowing gastric emptying and producing satiety). The GLP-1 receptor is the target of a class of research compounds including semaglutide, liraglutide, dulaglutide, and tirzepatide (which adds a GIP receptor arm) and retatrutide (which adds GIP and glucagon receptor arms).
- GlossaryIncretin
Gut-derived hormones (GLP-1, GIP) that stimulate post-meal insulin secretion.
- GlossaryGlucagon
A pancreatic hormone that opposes insulin — raises blood glucose, promotes lipolysis and ketogenesis.
- ResearchRetatrutide 40 mg pen
Retatrutide is a triple agonist at the GLP-1, GIP, and glucagon receptors. The 40 mg pen is the highest-dose presentation in the Omega Grade catalogue
- ResearchRetatrutide 30 mg kit
Retatrutide 30 mg lyophilised vial kit — the mid-dose research presentation. Includes bacteriostatic water, syringes, and swabs.
- ResearchRetatrutide 10 mg kit
Retatrutide 10 mg lyophilised vial kit — entry-point research presentation. Includes bac water, syringes, swabs.