IGF-1 LR3 1 mg — analytical-grade research peptideLong R3 IGF-1 · 1 mg / vial
Fig. 01 · Specimen
Lyophilised kit
In the box
  • ·3 mL bacteriostatic water
  • ·10 × 1 mL insulin syringes
  • ·Alcohol swabs
Growth hormoneClass IILong R3 IGF-1Long Arg3 IGF-1

IGF-1 LR3 1 mg

Modified IGF-1 — reduced IGFBP binding, ~83-residue analogue.

Long R3 IGF-1 — an engineered IGF-1 analogue with reduced affinity for IGF-binding proteins and extended plasma half-life. Widely used research reagent.

Designation
Long R3 IGF-1
CAS no.
946870-92-4
Molecular formula
C400H625N111O115S9
MW (Da)
9111.28
Residues
83
Purity
≥ 98.0%
Form
Lyophilised kit
Dose
1 mg / vial
Class
Class II
Dispatch · per unit
£65GBP
≈ €77 · 0.00120 BTC
1
In stock·Same-day dispatch (order by 09:30 UK)·Tracked24 Royal Mail £6.50·Not shipped to USA
Clinical status: Research reagent. Extensively used in cell-culture and in vivo research. No clinical approval.
§ A Overview

What the peptide is.

IGF-1 LR3 is a modified form of insulin-like growth factor 1 with an Arg3 substitution that reduces binding to IGF-binding proteins, and an N-terminal 13-residue extension derived from porcine GH. It is among the most commonly used IGF-1 analogues in muscle-biology and cell-culture research.

Proposed mechanism

IGF-1R-mediated signalling → PI3K/Akt and MAPK pathways. Reduced IGFBP binding increases free-IGF availability in target tissues.

§ B Laboratory handling

Reconstitution, storage, and handling.

Lab-technical guidance for the researcher handling the material. Not therapeutic dosing, not administration guidance — those are not within the scope of this supply.

Reconstitution
Recommended solvent
Dilute acetic acid (0.1 N) or bacteriostatic water (depending on research context)
Typical volume
1 mL
Notes
  • IGF-1 analogues are sensitive to pH — dilute acetic acid is the reference solvent for research.
  • Bac water is suitable for short-term reconstitution and most preclinical protocols.
Storage
Lyophilised
−20 °C, desiccated, protected from light. Stable at 15–25 °C for up to 30 days in transit.
Reconstituted
2–8 °C, original vial, consumed within 4 weeks.
Shelf life · sealed
24 months from date of manufacture when stored lyophilised at −20 °C.
Shelf life · reconstituted
Up to 4 weeks refrigerated.
Handling notes
  • Longer-chain peptide — gentle handling. Protect from agitation.
§ C Certificate of Analysis

This lot, documented.

Every shipment is accompanied by a signed four-page analytical report including the HPLC chromatogram, ESI-MS spectrum, purity calculation, and sample handling chain-of-custody.

The report you will receive is specific to the lot dispatched to you. The display below is a current representative example.

igf 1 lr3 1mg · batch.log
LIVE
04:22:11lot 26-04-A received ┈ 5.00 g
04:22:40weight check ┈ PASS ±0.4 mg
04:23:12sample → janoshik ┈ 50 mg
04:23:12tracking #jnk-9218334
05:18:03HPLC result ┈ 99.24 %
05:18:04MS obs 4729.42 Da ┈ PASS
05:18:05coa.pdf signed ┈ attached
05:18:06lot approved ┈ LIVE
janoshik.report.txt
SIGNED
REPORT ID     JA-26-04-012
SUBJECT       IGF-1 LR3 1 mg
DESIGNATION   Long R3 IGF-1
LOT           26-04-A
METHOD        RP-HPLC, ESI-MS
COLUMN        C18, 250 x 4.6 mm, 5 um
MOBILE PHASE  A: 0.1% TFA in H2O
              B: 0.1% TFA in ACN
GRADIENT      5 -> 65% B over 20 min
FLOW RATE     1.0 mL/min
DETECTION     UV 214 nm
INJECTION     20 uL @ 0.5 mg/mL
---
PURITY (A%)   98.00
MASS EXP.     9111.28 Da
MASS OBS.     9111.30 Da
---
CONCLUSION    Identity CONFIRMED · Purity PASS
SIGNED BY     J. Novak, MSc · Janoshik Analytical SVK
DATE          2026-04-11
representative chromatogram · A214 nmRT 8.42 min
Representative trace · Lot-specific COA included with every dispatch
purity≥ 98.0%
§ E Peer-reviewed studies

Research references for IGF-1 LR3 1 mg.

1 peer-reviewed publications. Links resolve to PubMed. DOIs are provided where available.

  1. [01]
    Francis GL, Upton FM, Ballard FJ, et al.

    Insulin-like growth factors 1 and 2 in bovine colostrum — Long R3 IGF-1 characterization

    Biochemical Journal · 1988
§ F Questions

About this peptide.

For general site, shipping, and payment questions see the full FAQ.

Q.Why "LR3" in the name?
A.Long Arg-3. "Long" refers to the 13-residue N-terminal extension; "Arg-3" is the amino-acid substitution at position 3 that reduces binding-protein affinity.
Research use only

This peptide is supplied by Omega Grade for in vitro laboratory research use. It is not a drug, food, cosmetic, or dietary supplement. It is not approved by the FDA, EMA, MHRA, PMDA, or any other regulatory authority for any therapeutic indication.

No claim of therapeutic benefit is made or implied. The material is not intended for human or veterinary consumption, administration, or any form of self-experimentation. By purchasing, you acknowledge the researcher terms and accept full responsibility for local import compliance and all handling.