GRF (1-29)
The biologically active 29-amino-acid N-terminal fragment of growth hormone-releasing hormone.
GRF (1-29), also written 'GHRH(1-29)', is the N-terminal 29-amino-acid fragment of the full 44-amino-acid GHRH peptide — the active region that binds the GHRH receptor. Most synthetic GHRH analogues (sermorelin, tesamorelin, CJC-1295, modified GRF 1-29) are based on this fragment with various modifications to extend stability or half-life. The fragment retains full bioactivity at the GHRH receptor; the C-terminal residues 30-44 are not required for receptor binding.
- GlossaryGLP-1
Glucagon-like peptide-1, an incretin hormone that regulates glucose and appetite.
- GlossaryGIP
Glucose-dependent insulinotropic polypeptide, an incretin hormone with metabolic and adipose effects.
- GlossaryGHRH
Growth hormone-releasing hormone, the hypothalamic peptide that triggers GH release.
- ResearchCJC-1295 no DAC 10 mg
CJC-1295 without DAC — short-acting modified GRF(1-29). Commonly used in preclinical GH-pulse research alongside ipamorelin.
- ResearchMOTS-c 40 mg
MOTS-c is a 16-residue peptide encoded in the mitochondrial 12S rRNA region. Described by the Cohen lab in 2015 — studied in metabolic and exercise bi