mTOR
Mechanistic target of rapamycin — a master regulator of cell growth, metabolism, and autophagy.
Mechanistic target of rapamycin (mTOR) is a serine/threonine kinase that integrates signals from nutrients, growth factors, and energy status to regulate cell growth, protein synthesis, lipid metabolism, and autophagy. mTOR exists in two complexes — mTORC1 (nutrient-sensing) and mTORC2 (growth factor signalling). Research interest in mTOR has surged because its inhibition (by rapamycin / sirolimus and the broader rapalog class) extends lifespan in multiple model organisms and is a leading longevity research target.
- GlossaryAutophagy
The cell's recycling process — sequestering and degrading damaged proteins and organelles.
- GlossaryAMPK
A cellular energy sensor — activated when ATP drops, promotes catabolic / energy-restoring pathways.
- GlossaryGLP-1
Glucagon-like peptide-1, an incretin hormone that regulates glucose and appetite.
- ResearchMOTS-c 40 mg
MOTS-c is a 16-residue peptide encoded in the mitochondrial 12S rRNA region. Described by the Cohen lab in 2015 — studied in metabolic and exercise bi
- ResearchNAD⁺ 500 mg kit
Nicotinamide adenine dinucleotide — the coenzyme central to cellular electron-transfer, sirtuin signalling, and redox biology.