Selank 11 mg
Also known as · Tuftsin analogue TP-7
Selank is a synthetic heptapeptide analogue of tuftsin. Registered in Russia as a non-benzodiazepine anxiolytic; Western research-use only.
Chemistry quick-facts
- CAS
- 129954-34-3
- Formula
- C33H57N11O9
- MW
- 751.87 Da
- Length
- 7 aa
- Status
- Registered for clinical use in Russia as an anxiolytic. No Western regulatory approval.
- Purity (HPLC)
- ≥ 99.0%
Mechanism of action
Proposed: GABAergic and enkephalin-system modulation, anxiolytic effects without sedation in preclinical studies.
Research context
Selank was developed as an analogue of tuftsin (an endogenous tetrapeptide from the Fc portion of IgG). The Pro-Gly-Pro C-terminal addition extends enzymatic stability.
Registered in Russia under the brand name Selank for generalised anxiety and related indications. Not approved elsewhere.
Published studies
A non-exhaustive list of peer-reviewed studies referenced when curating this entry. Click through to the primary source for the full text.
- Medvedev VE, Tereshchenko OP, Israelyan AY, et al. (2015). Optimization of treatment of anxiety with non-benzodiazepine anxiolytics selank and afobazole. Neuroscience and Behavioral Physiology.
Reconstitution
- Solvent
- Bacteriostatic water for injection (0.9% benzyl alcohol) — included with kit
- Typical volume
- 1 – 2 mL
- · Inject diluent slowly down the side of the vial onto the cake.
- · Swirl gently — do not shake.
- · Solution should be clear and colourless. Discard if not.
Storage
- Lyophilised
- −20 °C, desiccated, protected from light. Stable at 15–25 °C for up to 30 days in transit.
- Reconstituted
- 2–8 °C, original vial, consumed within 4 weeks.
- Shelf life — sealed
- 24 months from date of manufacture when stored lyophilised at −20 °C.
This page summarises the research literature on Selank 11 mg for in vitro laboratory investigation only. It is not medical advice, not a treatment recommendation, and not a substitute for a qualified physician. Material is sold for analytical chemistry and cell-culture research, not for human or veterinary administration.
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