SLU-PP-332 5 mg
Also known as · SLU-PP-332
SLU-PP-332 is a small-molecule pan-ERR (estrogen-related receptor) agonist developed by the Burris lab. Preclinical metabolic-research tool.
Chemistry quick-facts
- CAS
- 1334513-02-8
- Formula
- C18H13F3N2O3S
- MW
- 394.37 Da
- Status
- Preclinical research tool from the Burris laboratory. No clinical trials.
- Purity (HPLC)
- ≥ 98.0%
Mechanism of action
Pan-agonism at estrogen-related receptor family (ERRα / β / γ) → transcriptional activation of mitochondrial-biogenesis programmes.
Research context
SLU-PP-332 is a small-molecule agonist of the ERRα / β / γ nuclear receptors, developed by the Burris laboratory at Saint Louis University. Published preclinical work (2023) demonstrated metabolic effects in mice, including exercise-mimetic activity.
Published studies
A non-exhaustive list of peer-reviewed studies referenced when curating this entry. Click through to the primary source for the full text.
- Billon C, Sitaula S, Banerjee S, et al. (2023). Synthetic ERR agonists induce the phenotype of endurance exercise. Science Advances.
Reconstitution
- Solvent
- DMSO for in vitro stock solutions; aqueous co-solvent for in vivo
- Typical volume
- 1 mL
- · Small molecule — prepare cell-culture stock in DMSO per standard protocols.
Storage
- Lyophilised
- −20 °C, desiccated, protected from light. Stable at 15–25 °C for up to 30 days in transit.
- Reconstituted
- 2–8 °C, original vial, consumed within 4 weeks.
- Shelf life — sealed
- 24 months from date of manufacture when stored lyophilised at −20 °C.
This page summarises the research literature on SLU-PP-332 5 mg for in vitro laboratory investigation only. It is not medical advice, not a treatment recommendation, and not a substitute for a qualified physician. Material is sold for analytical chemistry and cell-culture research, not for human or veterinary administration.
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