Methylene Blue 100 mL / 30%
Also known as · Methylthioninium chloride
Methylene blue is a phenothiazine dye with extensive applications in cellular and mitochondrial research, histology, and redox biology.
Chemistry quick-facts
- CAS
- 61-73-4
- Formula
- C16H18ClN3S
- MW
- 319.85 Da
- Status
- Approved for methemoglobinemia treatment (IV, pharmaceutical grade only). Research-grade methylene blue is used extensively in cell biology, mitochondrial research, and neuroprotection studies.
- Purity (HPLC)
- ≥ 99.0%
Mechanism of action
Electron-cycling between oxidised (MB) and reduced (leucoMB) forms. Mitochondrial complex IV alternate electron acceptor; ROS-scavenging activity; NO-synthase inhibition.
Research context
Methylene blue (methylthioninium chloride) is one of the oldest synthetic dyes, first synthesised in 1876. Clinically approved for methemoglobinemia (IV administration) but widely used as a research reagent in cellular biology, mitochondrial-function studies, and neuroprotection research.
Omega Grade supplies a 30% w/v aqueous research-grade solution. Not the pharmaceutical-grade IV formulation.
Published studies
A non-exhaustive list of peer-reviewed studies referenced when curating this entry. Click through to the primary source for the full text.
- Rojas JC, Bruchey AK, Gonzalez-Lima F (2012). Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue. Progress in Neurobiology.
Reconstitution
- Solvent
- N/A — pre-formulated solution
- Typical volume
- N/A
- · 30% w/v aqueous solution in amber glass. Protect from light.
Storage
- Lyophilised
- Room temperature or 2–8 °C, amber glass, sealed.
- Reconstituted
- N/A — pre-formulated.
- Shelf life — sealed
- 24 months at room temperature.
FAQ
Why is this in a peptide catalogue?+
Methylene blue is commonly paired with mitochondrial peptides in bioenergetics and neuroprotection research. It is not a peptide — it is a phenothiazine dye.
This page summarises the research literature on Methylene Blue 100 mL / 30% for in vitro laboratory investigation only. It is not medical advice, not a treatment recommendation, and not a substitute for a qualified physician. Material is sold for analytical chemistry and cell-culture research, not for human or veterinary administration.
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